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RECEPTORS, FORMYL PEPTIDE
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DeCS
Descriptor
English
:
Receptors, Formyl Peptide
Descriptor
Spanish
:
Receptores de Formil Péptido
Descriptor
Portuguese
:
Receptores de Formil Peptídeo
Synonyms
English
:
Chemotactic Peptide Receptor
Tree Number:
D12.776.543.750.100.235
D12.776.543.750.705.873
D12.776.543.750.750.340
Definition
English
:
A
family
of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl
peptides
such as
N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE
. Since N-formyl
peptides
are found in
MITOCHONDRIA
and
BACTERIA
, this class of receptors is believed to play a
role
in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide
ligands
have also been found for this receptor class.
History Note
English
:
2004; use RECEPTORS, FORMYL PEPTIDE (NM) 1980-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
38276
Unique Identifier:
D044042
Occurrence in VHL
:
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